Immune-Epithelial Dynamics and Tissue Remodeling in Chronically Inflamed Nasal Epithelium via Multi-scaled Transcriptomics

Cell information vs gene expression on reduced dimensions

In this tab, users can visualise both cell information and gene expression side-by-side on low-dimensional representions.

Dimension Reduction

Cell information

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Cell numbers / statistics

Gene expression

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Cell information vs cell information on dimension reduction

In this tab, users can visualise two cell informations side-by-side on low-dimensional representions.

Dimension Reduction

Cell information 1

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Cell information 2

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Gene expression vs gene expression on dimension reduction

In this tab, users can visualise two gene expressions side-by-side on low-dimensional representions.

Dimension Reduction

Gene expression 1

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Gene expression 2

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Coexpression of two genes on reduced dimensions

In this tab, users can visualise the coexpression of two genes on low-dimensional representions.

Dimension Reduction

Gene Expression

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Cell information / gene expression violin plot / box plot

In this tab, users can visualise the gene expression or continuous cell information (e.g. Number of UMIs / module score) across groups of cells (e.g. libary / clusters).



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Proportion / cell numbers across different cell information

In this tab, users can visualise the composition of single cells based on one discrete cell information across another discrete cell information. Usage examples include the library or cellcycle composition across clusters.



Download PDF Download PNG

Gene expression bubbleplot / heatmap

In this tab, users can visualise the gene expression patterns of multiple genes grouped by categorical cell information (e.g. library / cluster).
The normalised expression are averaged, log-transformed and then plotted.




Download PDF Download PNG

Cell information vs gene expression on reduced dimensions

In this tab, users can visualise both cell information and gene expression side-by-side on low-dimensional representions.

Dimension Reduction

Cell information

Download PDF Download PNG

Cell numbers / statistics

Gene expression

Download PDF Download PNG

Cell information vs cell information on dimension reduction

In this tab, users can visualise two cell informations side-by-side on low-dimensional representions.

Dimension Reduction

Cell information 1

Download PDF Download PNG

Cell information 2

Download PDF Download PNG

Gene expression vs gene expression on dimension reduction

In this tab, users can visualise two gene expressions side-by-side on low-dimensional representions.

Dimension Reduction

Gene expression 1

Download PDF Download PNG

Gene expression 2

Download PDF Download PNG

Coexpression of two genes on reduced dimensions

In this tab, users can visualise the coexpression of two genes on low-dimensional representions.

Dimension Reduction

Gene Expression

Download PDF Download PNG

Cell information / gene expression violin plot / box plot

In this tab, users can visualise the gene expression or continuous cell information (e.g. Number of UMIs / module score) across groups of cells (e.g. libary / clusters).



Download PDF Download PNG

Proportion / cell numbers across different cell information

In this tab, users can visualise the composition of single cells based on one discrete cell information across another discrete cell information. Usage examples include the library or cellcycle composition across clusters.



Download PDF Download PNG

Gene expression bubbleplot / heatmap

In this tab, users can visualise the gene expression patterns of multiple genes grouped by categorical cell information (e.g. library / cluster).
The normalised expression are averaged, log-transformed and then plotted.




Download PDF Download PNG

Cell information vs gene expression on reduced dimensions

In this tab, users can visualise both cell information and gene expression side-by-side on low-dimensional representions.

Dimension Reduction

Cell information

Download PDF Download PNG

Cell numbers / statistics

Gene expression

Download PDF Download PNG

Cell information vs cell information on dimension reduction

In this tab, users can visualise two cell informations side-by-side on low-dimensional representions.

Dimension Reduction

Cell information 1

Download PDF Download PNG

Cell information 2

Download PDF Download PNG

Gene expression vs gene expression on dimension reduction

In this tab, users can visualise two gene expressions side-by-side on low-dimensional representions.

Dimension Reduction

Gene expression 1

Download PDF Download PNG

Gene expression 2

Download PDF Download PNG

Coexpression of two genes on reduced dimensions

In this tab, users can visualise the coexpression of two genes on low-dimensional representions.

Dimension Reduction

Gene Expression

Download PDF Download PNG

Cell information / gene expression violin plot / box plot

In this tab, users can visualise the gene expression or continuous cell information (e.g. Number of UMIs / module score) across groups of cells (e.g. libary / clusters).



Download PDF Download PNG

Proportion / cell numbers across different cell information

In this tab, users can visualise the composition of single cells based on one discrete cell information across another discrete cell information. Usage examples include the library or cellcycle composition across clusters.



Download PDF Download PNG

Gene expression bubbleplot / heatmap

In this tab, users can visualise the gene expression patterns of multiple genes grouped by categorical cell information (e.g. library / cluster).
The normalised expression are averaged, log-transformed and then plotted.




Download PDF Download PNG

Cell information vs gene expression on reduced dimensions

In this tab, users can visualise both cell information and gene expression side-by-side on low-dimensional representions.

Dimension Reduction

Cell information

Download PDF Download PNG

Cell numbers / statistics

Gene expression

Download PDF Download PNG

Cell information vs cell information on dimension reduction

In this tab, users can visualise two cell informations side-by-side on low-dimensional representions.

Dimension Reduction

Cell information 1

Download PDF Download PNG

Cell information 2

Download PDF Download PNG

Gene expression vs gene expression on dimension reduction

In this tab, users can visualise two gene expressions side-by-side on low-dimensional representions.

Dimension Reduction

Gene expression 1

Download PDF Download PNG

Gene expression 2

Download PDF Download PNG

Coexpression of two genes on reduced dimensions

In this tab, users can visualise the coexpression of two genes on low-dimensional representions.

Dimension Reduction

Gene Expression

Download PDF Download PNG

Cell information / gene expression violin plot / box plot

In this tab, users can visualise the gene expression or continuous cell information (e.g. Number of UMIs / module score) across groups of cells (e.g. libary / clusters).



Download PDF Download PNG

Proportion / cell numbers across different cell information

In this tab, users can visualise the composition of single cells based on one discrete cell information across another discrete cell information. Usage examples include the library or cellcycle composition across clusters.



Download PDF Download PNG

Gene expression bubbleplot / heatmap

In this tab, users can visualise the gene expression patterns of multiple genes grouped by categorical cell information (e.g. library / cluster).
The normalised expression are averaged, log-transformed and then plotted.




Download PDF Download PNG

GeoMX Image Visualization

In this tab, you can view GeoMX spatial images for different samples.



Current Sample:


            

Please contact Sizun Jiang at sjiang3@bidmc.harvard.edu if you have any questions about this repository. Please note the scripts here fall under an Academic usage license.

You can download the following single-cell RNA-seq Seurat object datasets:

Inhouse_scRNA_EpitheliumCells

Inhouse_scRNA_ImmuneCells

Nature_Immunology_data_Public_2022


You can also access the Digital Spatial Profiling (DSP) dataset:

Spatial Transcriptomics Data via Zenodo

This webpage was made using ShinyCell