General information
Overview

Data ID: AD00102

Species: Human

Region: Prefrontal cortex

Condition: Disease

Braak stage: "5-6"

Sex: Male

Age: 75-90+ years

Related datasets
Dataset information

Number of cells: 5103

Number of identified cell types: 7

Dataset source

Title: Single-cell Transcriptomic Analysis of Alzheimer's Disease

Methodology: Single-nucleus RNA-seq

Protocol: 10x Genomics

Public Data ID: syn18485175

Pubmed: 31042697

DOI: 10.1038/s41586-019-1195-2

Statement: The results published here are in whole or in part based on data obtained from the AD Knowledge Portal (https://adknowledgeportal.org). Samples for this study were provided by the Rush Alzheimer' Disease Center, Rush University Medical Center, Chicago. Data collection was supported through funding by NIA grants P30AG10161, R01AG15819, R01AG17917, R01AG30146, R01AG36836, U01AG32984, U01AG46152, the Illinois Department of Public Health, and the Translational Genomics Research Institute.

Cell clustering

Cell type & subcluster:

Total cells in the plot: 5103

Gene expression

Point size:

4

Please enter a gene symbol.

Differential expression (DE) / Gene set enrichment

Note: The MAST package were used to calculate DEGs on normalized gene expression data (parameter: log2FC > 0.25, adj.p-value < 0.05).

Group:

Find differentially expressed genes in each cell type by comparing it to all of the others.

Cell type of interest:

Log2 fold-change cutoff:

0.5

Adjusted p-value cutoff:

10^-6
10^-5
10^-4
10^-3
0.01
0.05
0.1
1
DE direction:

Total genes returned from query without filtering: 3089

Total genes in the table after filtering: 1

GPR98 2.2986 0.916 0.134 0.00e+0
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