Data ID: AD00104
Species: Human
Region: Prefrontal cortex
Condition: Disease
Braak stage: "5-6"
Sex: Male
Age: 75-90+ years
Number of cells: 8283
Number of identified cell types: 7
Title: Single-cell Transcriptomic Analysis of Alzheimer's Disease
Methodology: Single-nucleus RNA-seq
Protocol: 10x Genomics
Public Data ID: syn18485175
Pubmed: 31042697
DOI: 10.1038/s41586-019-1195-2
Statement: The results published here are in whole or in part based on data obtained from the AD Knowledge Portal (https://adknowledgeportal.org). Samples for this study were provided by the Rush Alzheimer' Disease Center, Rush University Medical Center, Chicago. Data collection was supported through funding by NIA grants P30AG10161, R01AG15819, R01AG17917, R01AG30146, R01AG36836, U01AG32984, U01AG46152, the Illinois Department of Public Health, and the Translational Genomics Research Institute.
Cell type & subcluster:
Total cells in the plot: 8283
Gene expression
Point size:
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Note: The MAST package were used to calculate DEGs on normalized gene expression data (parameter: log2FC > 0.25, adj.p-value < 0.05).
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Total genes returned from query without filtering: 2849
Total genes in the table after filtering: 7