Summary
Publication

Title: Spatial Transcriptomics Reveals Genes Associated with Dysregulated Mitochondrial Functions and Stress Signaling in Alzheimer Disease

Authors: Jos Fernndez Navarro, Deborah L Croteau, Aleksandra Jurek, Zaneta Andrusivova, Beimeng Yang, Yue Wang, Benjamin Ogedegbe, Tahira Riaz, Mari Sten, Claus Desler, Lene Juel Rasmussen, Tone Tnjum, Marie-Christine Galas, Joakim Lundeberg, Vilhelm A Bohr

Date published: 1/5/21

Date added: 5/1/22

Journal: iScience

DOI: 10.1016/j.isci.2020.101556

Protocol: ST

Data source: 10.17632/6s959w2zyr.1

Study design

Species: mouse

Number of samples: 48

Region: Hippocampus, olfactory bulb

Figure: Graphical abstract.

Spot-level data

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Total spots in the plot: 582

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Gene expression

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Spatially variable genes

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Foldchange direction:
Differential expression (DE) / Gene set enrichment

Sample:

Note: The MAST package were used to calculate DEGs on normalized gene expression data (parameter: log2FC > 0.25, adj.p-value < 0.05).

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0.5

Adjusted p-value cutoff:

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