Summary
Publication

Title: Clonal relations in the mouse brain revealed by single-cell and spatial transcriptomics

Authors: Michael Ratz, Leonie von Berlin, Ludvig Larsson, Marcel Martin, Jakub Orzechowski Westholm, Gioele La Manno, Joakim Lundeberg & Jonas Frisn

Date published: 2/24/22

Date added: 5/1/22

Journal: Nature Neuroscience

DOI: 10.1038/s41593-022-01011-x

Protocol: 10x Genomics Visium

Data source: See paper

Study design

Species: mouse

Number of samples: 8

Region: Whole brain, hippocampus

Figure: TREX enables simultaneous profiling of cell phenotype and clonality..

Spot-level data

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Total spots in the plot: 582

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Gene expression

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Spatially variable genes

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Differential expression (DE) / Gene set enrichment

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Note: The MAST package were used to calculate DEGs on normalized gene expression data (parameter: log2FC > 0.25, adj.p-value < 0.05).

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