Summary
Publication

Title: A spatially resolved brain region- and cell type-specific isoform atlas of the postnatal mouse brain

Authors: Anoushka Joglekar, Andrey Prjibelski, Ahmed Mahfouz, Paul Collier, Susan Lin, Anna Katharina Schlusche, Jordan Marrocco, Stephen R. Williams, Bettina Haase, Ashley Hayes, Jennifer G. Chew, Neil I. Weisenfeld, Man Ying Wong, Alexander N. Stein, Simon A. Hardwick, Toby Hunt, Qi Wang, Christoph Dieterich, Zachary Bent, Olivier Fedrigo, Steven A. Sloan, Davide Risso, Erich D. Jarvis, Paul Flicek, Hagen U. Tilgner

Date published: 1/19/21

Date added: 5/1/22

Journal: Nature Communications

DOI: 10.1038/s41467-020-20343-5

Protocol: 10x Genomics Visium

Data source: GSE158450

Study design

Species: mouse

Number of samples: 11

Region: Whole brain

Figure: Short read clustering of P7 hippocampus and prefrontal cortex tissue recovers precursors to known adult cell-types..

Spot-level data

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Total spots in the plot: 582

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Gene expression

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Spatially variable genes

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Differential expression (DE) / Gene set enrichment

Sample:

Note: The MAST package were used to calculate DEGs on normalized gene expression data (parameter: log2FC > 0.25, adj.p-value < 0.05).

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