ssread - ssREAD

Summary

Publication

Title: Moxibustion improves hypothalamus Aqp4 polarization in APP/PS1 mice: Evidence from spatial transcriptomics

Authors: Shuqing Liu, Hongying Li, Yuan Shen, Weikang Zhu, Yong Wang, Junmeng Wang, Ning Zhang, Chenyu Li, Lushuang Xie, Qiaofeng Wu

Date published: 2/2/23

Date added: 6/1/23

Journal: Frontiers in Aging Neuroscience

DOI: 10.3389/fnagi.2023.1069155

Protocol: 10x Genomics Visium

Data source: GSE222981

Study design

Species: mouse

Number of samples: 3

Region: Whole brain

Figure: Moxibustion rescued defects in memory and spatial transcriptomic (ST) characteristic distribution in APP/PS1 mice.

Spot-level data

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Total spots in the plot: 582

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Gene expression

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Spatially variable genes

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SLC1A2	2.86093	0.00e+0	0.978	0.325	0.114	1.956	1.625
ADGRV1	2.59936	0.00e+0	0.935	0.115	0.040	1.87	0.575
ATP1A2	2.46121	0.00e+0	0.975	0.201	0.070	1.95	1.005
GJA1	2.41141	0.00e+0	0.878	0.071	0.025	1.756	0.355
AQP4	2.3238	0.00e+0	0.887	0.126	0.044	1.774	0.630
ATP1B2	2.27351	0.00e+0	0.897	0.166	0.058	1.794	0.830
COL5A3	2.19993	0.00e+0	0.840	0.080	0.028	1.68	0.400
GLUL	2.1838	0.00e+0	0.944	0.291	0.102	1.888	1.455
SLC25A18	2.0364	0.00e+0	0.836	0.065	0.023	1.672	0.325
FGFR3	2.00915	0.00e+0	0.824	0.040	0.014	1.648	0.200
RYR3	1.9492	0.00e+0	0.841	0.083	0.029	1.682	0.415
SDC4	1.9286	0.00e+0	0.745	0.021	0.007	1.49	0.105
TPD52L1	1.92438	0.00e+0	0.786	0.065	0.023	1.572	0.325
CLU	1.89695	0.00e+0	0.973	0.584	0.204	1.946	2.920
SLC14A1	1.89389	0.00e+0	0.690	0.020	0.007	1.38	0.100

Differential expression (DE) / Gene set enrichment