Summary
Publication

Title: Multi-transcriptomics reveals brain cellular responses to peripheral infection in Alzheimers disease model mice

Authors: Yi Lu, Carolina Saibro-Girardi, Nicholas Francis Fitz, Mikayla Ranae McGuire, Mary Ann Ostach, A N M Mamun-Or-Rashid, Iliya Lefterov, Radosveta Koldamova

Date published: 7/25/23

Date added: 12/1/23

Journal: Cell Reports

DOI: 10.1016/j.celrep.2023.112785

Protocol: 10x Genomics Visium

Data source: GSE218360

Study design

Species: mouse

Number of samples: 8

Region: Whole brain

Figure: Graphical abstract

Spot-level data

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Total spots in the plot: 582

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Gene expression

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Spatially variable genes

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Foldchange direction:
Differential expression (DE) / Gene set enrichment

Sample:

Note: The MAST package were used to calculate DEGs on normalized gene expression data (parameter: log2FC > 0.25, adj.p-value < 0.05).

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0.5

Adjusted p-value cutoff:

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DE direction:
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