Summary
Publication

Title: Integrative in situ mapping of single-cell transcriptional states and tissue histopathology in a mouse model of Alzheimers disease

Authors: Hu Zeng, Jiahao Huang, Haowen Zhou, William J Meilandt, Borislav Dejanovic, Yiming Zhou, Christopher J Bohlen, Seung-Hye Lee, Jingyi Ren, Albert Liu, Zefang Tang, Hao Sheng, Jia Liu, Morgan Sheng, Xiao Wang

Date published: 2/2/23

Date added: 12/1/23

Journal: Nature Neuroscience

DOI: 10.1038/s41593-022-01251-x

Protocol: STARmap PLUS

Data source: SCP1375

Study design

Species: mouse

Number of samples: 12

Region: Hippocampus, cerebellum

Figure: Simultaneous mapping of cell types, single-cell transcriptional states and tissue histopathology by STARmap PLUS.

Spot-level data

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Total spots in the plot: 582

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Gene expression

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Spatially variable genes

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Differential expression (DE) / Gene set enrichment

Sample:

Note: The MAST package were used to calculate DEGs on normalized gene expression data (parameter: log2FC > 0.25, adj.p-value < 0.05).

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